Nabla Bio
Designing antibodies with atomic precision
Description
Nabla Bio is a biotechnology company specializing in the design of novel antibodies using a synergistic approach that combines artificial intelligence with advanced experimental methods. Founded by pioneers in protein language modeling, the company develops sophisticated generative models to design antibodies with atomic precision. This AI-guided design process is closely integrated with high-throughput wet-lab capabilities, including multiplexed screens and protein characterization technologies.
This integrated platform enables Nabla Bio to tackle historically challenging disease targets, such as G protein-coupled receptors (GPCRs) and ion channels. By combining computational power with empirical measurement of human-relevant drug properties, the company aims to create therapeutic antibodies with superior manufacturability, safety, and efficacy. Nabla Bio collaborates with leading pharmaceutical companies to translate these AI-designed drugs into treatments for patients with unmet medical needs.
Key Features
- Generative Models: AI models specifically developed for de novo antibody design.
- Integrated AI & Wet-Lab Platform: Combines computational design with empirical measurement and validation.
- Multiplexed Screens: High-throughput experimental screening capabilities.
- Protein Characterization: Advanced technologies for analyzing designed protein properties.
- Challenging Target Focus: Specializes in designing antibodies for difficult targets like GPCRs and ion channels.
- Protein Language Modeling Expertise: Founded by pioneers in the field.
Use Cases
- Designing novel therapeutic antibodies.
- Developing drugs for challenging disease targets (e.g., GPCRs, ion channels).
- Improving antibody manufacturability, safety, and efficacy.
- Accelerating pharmaceutical drug discovery pipelines.
- Overcoming limitations in targeting specific protein classes.
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